› 2wa5

X-ray diffraction
1.9Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130920 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Filamin-B Chain: A
Molecule details ›
Chain: A
Length: 245 amino acids
Theoretical weight: 28.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O75369 (Residues: 2-242; Coverage: 9%)
Gene names: FLN1L, FLN3, FLNB, TABP, TAP
Sequence domains: Calponin homology (CH) domain
Structure domains: Calponin-like domain

Ligands and Environments

2 bound ligands:
Ligand SO4 1 x SO4
Ligand CO3 4 x CO3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P212121
Unit cell:
a: 43.05Å b: 71.183Å c: 90.436Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 0.191 0.216
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

7 review citations

Filamins in mechanosensing and signaling.
Razinia et al. (2012)
6 more

3 mentions without citation

Structural and functional evaluation of C. elegans filamins FLN-1 and FLN-2.
DeMaso et al. (2011)
2 more