Function and Biology Details
Reaction catalysed:
ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Leucine--tRNA ligase, cytoplasmic (preferred)
PDBe Complex ID:
PDB-CPX-192840 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Leucine--tRNA ligase, cytoplasmic
Molecule details ›
Chains: A, B
Length: 252 amino acids
Theoretical weight: 28.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: tRNA synthetases class I (I, L, M and V)
Structure domains: Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
Length: 252 amino acids
Theoretical weight: 28.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q9P2J5 (Residues: 258-509; Coverage: 21%)
Sequence domains: tRNA synthetases class I (I, L, M and V)
Structure domains: Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
