› 2wg7

X-ray diffraction
2Å resolution

Structure of Oryza Sativa (Rice) PLA2

Released:
DOI: 10.2210/pdb2wg7/pdb
Model geometry
Fit model/data
PDB entry 2wg7 coloured by chain, front view.
PDB entry 2wg7 coloured by chain, side view.
PDB entry 2wg7 coloured by chain, top view.
Source organism: Oryza sativa
Primary publication:
Crystal structure of a class XIB phospholipase A2 (PLA2): rice (oryza sativa) isoform-2 pla2 and an octanoate complex.
Guy JE, Ståhl U, Lindqvist Y
J Biol Chem 284 19371-9 (2009)
PMID: 19457861

Function and Biology Details

Reaction catalysed: 
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195017 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Probable phospholipase A2 homolog 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 130 amino acids
Theoretical weight: 13.98 KDa
Source organism: Oryza sativa
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9XG81 (Residues: 25-153; Coverage: 100%)
Gene names: LOC_Os03g15460, Os03g0261100, OsJ_10213, PLA2-II
Structure domains: Phospholipase A2 domain

Ligands and Environments

2 bound ligands:
Ligand CA 2 x CA
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ESRF BEAMLINE ID23-2, ESRF BEAMLINE BM14
Spacegroup: P62
Unit cell:
a: 108.667Å b: 108.667Å c: 41.652Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.187 0.185 0.23
Expression system: Escherichia coli

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Citations

2 review citations

Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention.
Dennis et al. (2011)
1 more

4 mentions without citation

Carboxylic ester hydrolases: Classification and database derived from their primary, secondary, and tertiary structures.
Chen et al. (2016)
3 more