› 2wk7

X-ray diffraction
2.5Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191957 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CAI-1 autoinducer synthase Chains: A, B
Molecule details ›
Chains: A, B
Length: 393 amino acids
Theoretical weight: 43.97 KDa
Source organism: Vibrio cholerae O1 biovar El Tor str. N16961
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9KM65 (Residues: 1-389; Coverage: 100%)
Gene names: VC_A0523, cqsA
Sequence domains: Aminotransferase class I and II
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21212
Unit cell:
a: 177.314Å b: 70.077Å c: 70.703Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.206 0.286
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

7 review citations

Quorum sensing and bacterial biofilms.
Dickschat JS. (2010)
6 more

2 mentions without citation

Noncanonical Functions of Enzyme Cofactors as Building Blocks in Natural Product Biosynthesis.
Barra et al. (2022)
1 more