› 2wl8

X-ray diffraction
2.05Å resolution

X-ray crystal structure of Pex19p

Released:
DOI: 10.2210/pdb2wl8/pdb
PDB entry 2wl8 coloured by chain, front view.
PDB entry 2wl8 coloured by chain, side view.
PDB entry 2wl8 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The peroxisomal receptor Pex19p forms a helical mPTS recognition domain.
Schueller N, Holton SJ, Fodor K, Milewski M, Konarev P, Stanley WA, Wolf J, Erdmann R, Schliebs W, Song YH, Wilmanns M
EMBO J 29 2491-500 (2010)
PMID: 20531392

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154197 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxisomal biogenesis factor 19 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 126 amino acids
Theoretical weight: 14.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P40855 (Residues: 161-283; Coverage: 41%)
Gene names: HK33, OK/SW-cl.22, PEX19, PXF
Sequence domains: Pex19 protein family
Structure domains: Pex19, mPTS binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7A
Spacegroup: P212121
Unit cell:
a: 67.15Å b: 91.12Å c: 122.287Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.199 0.239
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

12 review citations

Lipid droplets and peroxisomes: key players in cellular lipid homeostasis or a matter of fat--store 'em up or burn 'em down.
Kohlwein et al. (2013)
11 more

3 mentions without citation

Towards the molecular mechanism of the integration of peroxisomal membrane proteins.
Giannopoulou et al. (2016)
2 more