2wrg

X-ray diffraction
3Å resolution

structure of H1 1918 hemagglutinin with human receptor

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-194354 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Hemagglutinin HA1 chain Chains: H, J, L
Molecule details ›
Chains: H, J, L
Length: 326 amino acids
Theoretical weight: 36 KDa
Source organism: Influenza A virus (A/Brevig Mission/1/1918(H1N1))
UniProt:
  • Canonical: Q9WFX3 (Residues: 18-343; Coverage: 59%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains:
Hemagglutinin HA2 chain Chains: I, K, M
Molecule details ›
Chains: I, K, M
Length: 222 amino acids
Theoretical weight: 25.05 KDa
Source organism: Influenza A virus (A/Brevig Mission/1/1918(H1N1))
UniProt:
  • Canonical: Q9WFX3 (Residues: 345-566; Coverage: 40%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, GAL, SIA
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 104.758Å b: 156.843Å c: 157.842Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.27 0.268 0.308