› 2wrt

X-ray diffraction
2.4Å resolution

The 2.4 Angstrom structure of the Fasciola hepatica mu class GST, GST26

Released:
DOI: 10.2210/pdb2wrt/pdb
PDB entry 2wrt coloured by chain, front view.
PDB entry 2wrt coloured by chain, side view.
PDB entry 2wrt coloured by chain, top view.
Source organism: Fasciola hepatica
Entry authors: Line K, Isupov MN, LaCourse EJ, Brophy PM, Littlechild JA

Function and Biology Details

Reaction catalysed: 
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151636 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase class-mu 26 kDa isozyme 51 Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 218 amino acids
Theoretical weight: 25.35 KDa
Source organism: Fasciola hepatica
Expression system: Escherichia coli
UniProt:
  • Canonical: P30112 (Residues: 1-218; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CL 12 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21
Unit cell:
a: 92.31Å b: 92.501Å c: 166.422Å
α: 90° β: 94.55° γ: 90°
R-values:
R R work R free
0.209 0.205 0.281
Expression system: Escherichia coli

Quick links