› 2wzo

X-ray diffraction
1.6Å resolution

The structure of the FYR domain

Released:
DOI: 10.2210/pdb2wzo/pdb
PDB entry 2wzo coloured by chain, front view.
PDB entry 2wzo coloured by chain, side view.
PDB entry 2wzo coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The structure of the FYR domain of transforming growth factor beta regulator 1.
García-Alai MM, Allen MD, Joerger AC, Bycroft M
Protein Sci 19 1432-8 (2010)
PMID: 20506279

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174891 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transforming growth factor beta regulator 1 Chain: A
Molecule details ›
Chain: A
Length: 146 amino acids
Theoretical weight: 15.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q3YBR2 (Residues: 179-324; Coverage: 36%)
Gene names: NIAM, TBRG1
Sequence domains:
Structure domains: Double Stranded RNA Binding Domain

Ligands and Environments

1 bound ligand:
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P3121
Unit cell:
a: 53.867Å b: 53.867Å c: 91.297Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.179 0.178 0.202
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

9 review citations

The super elongation complex (SEC) and MLL in development and disease.
Smith et al. (2011)
8 more

4 mentions without citation

The structure of the FYR domain of transforming growth factor beta regulator 1.
García-Alai et al. (2010)
3 more