› 2x3v

X-ray diffraction
2.45Å resolution

Structure of The F-BAR Domain of Mouse Syndapin I

Released:
DOI: 10.2210/pdb2x3v/pdb
PDB entry 2x3v coloured by chain, front view.
PDB entry 2x3v coloured by chain, side view.
PDB entry 2x3v coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Molecular basis for SH3 domain regulation of F-BAR-mediated membrane deformation.
Rao Y, Ma Q, Vahedi-Faridi A, Sundborger A, Pechstein A, Puchkov D, Luo L, Shupliakov O, Saenger W, Haucke V
Proc Natl Acad Sci U S A 107 8213-8 (2010)
PMID: 20404169

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178896 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein kinase C and casein kinase substrate in neurons protein 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 337 amino acids
Theoretical weight: 39.35 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q61644 (Residues: 1-337; Coverage: 76%)
Gene names: Pacsin, Pacsin1
Sequence domains: Fes/CIP4, and EFC/F-BAR homology domain
Structure domains: Arfaptin homology (AH) domain/BAR domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: C2221
Unit cell:
a: 85.06Å b: 153.49Å c: 213.29Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.212 0.26
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

22 review citations

Dynamin, a membrane-remodelling GTPase.
Ferguson et al. (2012)
21 more

3 mentions without citation

Molecular basis for SH3 domain regulation of F-BAR-mediated membrane deformation.
Rao et al. (2010)
2 more