Function and Biology Details
Reaction catalysed:
Converts human Glu-plasminogen to plasmin by cleaving the 560-Arg-|-Val-561 peptide bond that is also hydrolyzed by the mammalian u-plasminogen activator and t-plasminogen activator. Also cleaves arginyl bonds in other proteins.
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Plasminogen activator (preferred)
PDBe Complex ID:
PDB-CPX-148182 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Plasminogen activator
Molecule details ›
Chains: A, B, C, D
Length: 298 amino acids
Theoretical weight: 32.95 KDa
Source organism: Yersinia pestis
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Omptin family
Structure domains: OMPT-like
Length: 298 amino acids
Theoretical weight: 32.95 KDa
Source organism: Yersinia pestis
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P17811 (Residues: 21-312; Coverage: 100%)
Sequence domains: Omptin family
Structure domains: OMPT-like
