› 2x6c

X-ray diffraction
2.7Å resolution

Potassium Channel from Magnetospirillum Magnetotacticum

Released:
DOI: 10.2210/pdb2x6c/pdb
PDB entry 2x6c coloured by chain, front view.
PDB entry 2x6c coloured by chain, side view.
PDB entry 2x6c coloured by chain, top view.
Source organism: Magnetospirillum magnetotacticum
Primary publication:
Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels.
Clarke OB, Caputo AT, Hill AP, Vandenberg JI, Smith BJ, Gulbis JM
Cell 141 1018-29 (2010)
PMID: 20564790

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-112991 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inward rectifier potassium channel Kirbac3.1 Chain: A
Molecule details ›
Chain: A
Length: 301 amino acids
Theoretical weight: 33.73 KDa
Source organism: Magnetospirillum magnetotacticum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: D9N164 (Residues: 1-295; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand PC 1 x PC
Ligand SM 4 x SM
Ligand K 10 x K
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P4212
Unit cell:
a: 106.518Å b: 106.518Å c: 88.854Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.219 0.261
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

15 review citations

GPCR mediated regulation of synaptic transmission.
Betke et al. (2012)
14 more

2 mentions without citation

Structure of potassium channels.
Kuang et al. (2015)
1 more