Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
TRIM5alpha and Gag protein (preferred)
PDBe Complex ID:
PDB-CPX-109277 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Gag protein
Molecule details ›
Chains: A, C
Length: 146 amino acids
Theoretical weight: 16.2 KDa
Source organism: Human immunodeficiency virus type 1 lw12.3 isolate
Expression system: Escherichia coli
UniProt:
Sequence domains: gag protein p24 N-terminal domain
Structure domains: Human Immunodeficiency Virus Type 1 Capsid Protein
Length: 146 amino acids
Theoretical weight: 16.2 KDa
Source organism: Human immunodeficiency virus type 1 lw12.3 isolate
Expression system: Escherichia coli
UniProt:
- Canonical:
E9MJX7 (Residues: 125-270; Coverage: 43%)
Sequence domains: gag protein p24 N-terminal domain
Structure domains: Human Immunodeficiency Virus Type 1 Capsid Protein
TRIM5alpha
Molecule details ›
Chains: B, D
Length: 163 amino acids
Theoretical weight: 17.76 KDa
Source organism: Macaca fascicularis
Expression system: Escherichia coli BL21(DE3)
UniProt:
Structure domains: Cyclophilin-like
Length: 163 amino acids
Theoretical weight: 17.76 KDa
Source organism: Macaca fascicularis
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: B0ZE32 (Residues: 304-466; Coverage: 35%)
Structure domains: Cyclophilin-like
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU FR-E SUPERBRIGHT
Spacegroup:
P21
Expression systems:
- Escherichia coli
- Escherichia coli BL21(DE3)
