› 2x8a

X-ray diffraction
2.6Å resolution

Human Nuclear Valosin containing protein Like (NVL), C-terminal AAA- ATPase domain

Released:
DOI: 10.2210/pdb2x8a/pdb
PDB entry 2x8a coloured by chain, front view.
PDB entry 2x8a coloured by chain, side view.
PDB entry 2x8a coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Moche M, Schuetz P, Arrowsmith CH, Berglund H, Bountra C, Collins R, Edwards AM, Flodin S, Flores A, Graslund S, Hammarstrom M, Johansson I, Kallas A, Karlberg T, Kotenyova T, Kraulis P, Nordlund P, Nyman T, Persson C, Sehic A, Siponen MI, Svensson L, Thorsell AG, Tresaugues L, VanDenBerg S, Wahlberg E, Weigelt J, Welin M, Wisniewska M, Schuler H

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127451 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nuclear valosin-containing protein-like Chain: A
Molecule details ›
Chain: A
Length: 274 amino acids
Theoretical weight: 29.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O15381 (Residues: 573-845; Coverage: 32%)
Gene names: NVL, NVL2
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P61
Unit cell:
a: 77.989Å b: 77.989Å c: 86.038Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.214 0.21 0.25
Expression system: Escherichia coli BL21(DE3)

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