› 2x8u

X-ray diffraction
2.1Å resolution

Sphingomonas wittichii Serine palmitoyltransferase

Released:
DOI: 10.2210/pdb2x8u/pdb
PDB entry 2x8u coloured by chain, front view.
PDB entry 2x8u coloured by chain, side view.
PDB entry 2x8u coloured by chain, top view.
Source organism: Rhizorhabdus wittichii RW1
Primary publication:
The serine palmitoyltransferase from Sphingomonas wittichii RW1: An interesting link to an unusual acyl carrier protein.
Raman MC, Johnson KA, Clarke DJ, Naismith JH, Campopiano DJ
Biopolymers 93 811-22 (2010)
PMID: 20578000

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163310 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SERINE PALMITOYLTRANSFERASE Chains: A, B
Molecule details ›
Chains: A, B
Length: 412 amino acids
Theoretical weight: 44.54 KDa
Source organism: Rhizorhabdus wittichii RW1
Expression system: Escherichia coli
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand PLP 2 x PLP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P31
Unit cell:
a: 99.37Å b: 99.37Å c: 72.66Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.164 0.163 0.196
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Bacterial membrane lipids: diversity in structures and pathways.
Sohlenkamp et al. (2016)
5 more

2 mentions without citation

Sphingolipid biosynthesis in man and microbes.
Harrison et al. (2018)
1 more