› 2xa6

Solution NMR

Structural basis for homodimerization of the Src-associated during mitosis, 68 kD protein (Sam68) Qua1 domain

Released:
DOI: 10.2210/pdb2xa6/pdb
PDB entry 2xa6 coloured by chain, ensemble of 20 models, front view.
PDB entry 2xa6 coloured by chain, ensemble of 20 models, side view.
PDB entry 2xa6 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for homodimerization of the Src-associated during mitosis, 68-kDa protein (Sam68) Qua1 domain.
Meyer NH, Tripsianes K, Vincendeau M, Madl T, Kateb F, Brack-Werner R, Sattler M
J Biol Chem 285 28893-901 (2010)
PMID: 20610388

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170491 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
KH domain-containing, RNA-binding, signal transduction-associated protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 41 amino acids
Theoretical weight: 4.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07666 (Residues: 97-135; Coverage: 9%)
Gene names: KHDRBS1, SAM68
Sequence domains: Qua1 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 48%
Refinement method: CYANA, ARIA
Expression system: Escherichia coli

Quick links

Citations

7 review citations

NMR approaches for structural analysis of multidomain proteins and complexes in solution.
Göbl et al. (2014)
6 more

6 mentions without citation

Protein-Protein Interactions Mediated by Helical Tertiary Structure Motifs.
Watkins et al. (2015)
5 more