› 2xb4

X-ray diffraction
1.8Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + AMP = 2 ADP
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111780 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenylate kinase Chain: A
Molecule details ›
Chain: A
Length: 223 amino acids
Theoretical weight: 24.53 KDa
Source organism: Megalodesulfovibrio gigas
UniProt:
  • Canonical: C7U112 (Residues: 1-223; Coverage: 100%)
Gene names: adk, ak
Sequence domains: Adenylate kinase
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand ZN 1 x ZN
Ligand SRT 1 x SRT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: I222
Unit cell:
a: 39.39Å b: 119.44Å c: 149.59Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.178 0.212

Quick links

Citations

1 review citation

Normal Mode Analysis as a Routine Part of a Structural Investigation.
Bauer et al. (2019)
5 other articles

1 mention without citation

Conformational heterogeneity within the LID domain mediates substrate binding to Escherichia coli adenylate kinase: function follows fluctuations.
Schrank et al. (2013)