Function and Biology Details
Reaction catalysed:
ATP-dependent breakage, passage and rejoining of double-stranded DNA
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- DNA topoisomerase, type IIA, domain A
- DNA topoisomerase, type IIA, subunit B
- TOPRIM domain
- DNA topoisomerase, type IIA, alpha-helical domain superfamily
- DNA topoisomerase, type IIA, domain A, alpha-beta
- DNA gyrase B subunit, C-terminal
- DNA topoisomerase, type IIA, conserved site
- DNA gyrase subunit B, TOPRIM domain
3 more domains
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
DNA gyrase subunit A, DNA gyrase subunit B (preferred)
PDBe Complex ID:
PDB-CPX-159193 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA gyrase subunit A; DNA gyrase subunit B
Molecule details ›
Chain: A
Length: 726 amino acids
Theoretical weight: 82.34 KDa
Source organism: Staphylococcus aureus subsp. aureus N315
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains:
Length: 726 amino acids
Theoretical weight: 82.34 KDa
Source organism: Staphylococcus aureus subsp. aureus N315
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P66937 (Residues: 410-644; Coverage: 37%) - Canonical: Q99XG5 (Residues: 2-491; Coverage: 55%)
Sequence domains:
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID14-4
Spacegroup:
P6122
Expression system: Escherichia coli BL21(DE3)
