Function and Biology Details
Reaction catalysed:
ATP-dependent breakage, passage and rejoining of double-stranded DNA
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- DNA topoisomerase, type IIA, domain A
- TOPRIM domain
- DNA topoisomerase, type IIA, alpha-helical domain superfamily
- DNA topoisomerase, type IIA, domain A, alpha-beta
- DNA gyrase B subunit, C-terminal
- DNA topoisomerase, type IIA, conserved site
- DNA gyrase subunit B, TOPRIM domain
- DNA topoisomerase, type IIA-like domain superfamily
2 more domains
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115924 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
DNA gyrase subunit A; DNA gyrase subunit B
Molecule details ›
Chains: B, D
Length: 692 amino acids
Theoretical weight: 78.11 KDa
Source organism: Staphylococcus aureus subsp. aureus N315
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains: Rossmann fold
Length: 692 amino acids
Theoretical weight: 78.11 KDa
Source organism: Staphylococcus aureus subsp. aureus N315
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P66937 (Residues: 410-543, 580-644; Coverage: 31%) - Canonical: Q99XG5 (Residues: 2-491; Coverage: 55%)
Sequence domains:
Structure domains: Rossmann fold
