› 2xgu

X-ray diffraction
1.5Å resolution

Structure of the N-terminal domain of capsid protein from Rabbit Endogenous Lentivirus (RELIK)

Released:
DOI: 10.2210/pdb2xgu/pdb
PDB entry 2xgu coloured by chain, front view.
PDB entry 2xgu coloured by chain, side view.
PDB entry 2xgu coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
Structural and functional analysis of prehistoric lentiviruses uncovers an ancient molecular interface.
Goldstone DC, Yap MW, Robertson LE, Haire LF, Taylor WR, Katzourakis A, Stoye JP, Taylor IA
Cell Host Microbe 8 248-59 (2010)
PMID: 20833376

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163322 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RELIK CAPSID N-TERMINAL DOMAIN Chains: A, B
Molecule details ›
Chains: A, B
Length: 149 amino acids
Theoretical weight: 16.51 KDa
Source organism: Oryctolagus cuniculus
Expression system: Escherichia coli BL21(DE3)
Structure domains: Human Immunodeficiency Virus Type 1 Capsid Protein

Ligands and Environments

1 bound ligand:
Ligand ACT 1 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: C2
Unit cell:
a: 87Å b: 38.68Å c: 84.717Å
α: 90° β: 114.87° γ: 90°
R-values:
R R work R free
0.196 0.195 0.218
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

13 review citations

Endogenous viruses: insights into viral evolution and impact on host biology.
Feschotte et al. (2012)
12 more

3 mentions without citation

A comparative analysis of the foamy and ortho virus capsid structures reveals an ancient domain duplication.
Taylor et al. (2017)
2 more