› 2xgv

X-ray diffraction
2Å resolution

Structure of the N-terminal domain of capsid protein from Rabbit Endogenous Lentivirus (RELIK)

Released:
DOI: 10.2210/pdb2xgv/pdb
PDB entry 2xgv coloured by chain, front view.
PDB entry 2xgv coloured by chain, side view.
PDB entry 2xgv coloured by chain, top view.
Source organism: Microcebus murinus
Primary publication:
Structural and functional analysis of prehistoric lentiviruses uncovers an ancient molecular interface.
Goldstone DC, Yap MW, Robertson LE, Haire LF, Taylor WR, Katzourakis A, Stoye JP, Taylor IA
Cell Host Microbe 8 248-59 (2010)
PMID: 20833376

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163323 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PSIV CAPSID N-TERMINAL DOMAIN Chain: A
Molecule details ›
Chain: A
Length: 142 amino acids
Theoretical weight: 15.99 KDa
Source organism: Microcebus murinus
Expression system: Escherichia coli
Structure domains: Human Immunodeficiency Virus Type 1 Capsid Protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 80.25Å b: 62.71Å c: 26.87Å
α: 90° β: 102.11° γ: 90°
R-values:
R R work R free
0.186 0.184 0.224
Expression system: Escherichia coli

Quick links

Citations

13 review citations

Endogenous viruses: insights into viral evolution and impact on host biology.
Feschotte et al. (2012)
12 more

2 mentions without citation

A comparative analysis of the foamy and ortho virus capsid structures reveals an ancient domain duplication.
Taylor et al. (2017)
1 more