› 2xio

X-ray diffraction
1.19Å resolution

Structure of putative deoxyribonuclease TATDN1 isoform a

Released:
DOI: 10.2210/pdb2xio/pdb
PDB entry 2xio coloured by chain, front view.
PDB entry 2xio coloured by chain, side view.
PDB entry 2xio coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Muniz JRC, Cocking R, Puranik S, Krojer T, Raynor J, Vollmar M, von Delft F, Arrowsmith CH, Edwards AM, Weigelt J, Bountra C, Yue WW, Kavanagh KL, Oppermann U

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180103 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Deoxyribonuclease TATDN1 Chain: A
Molecule details ›
Chain: A
Length: 301 amino acids
Theoretical weight: 34.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6P1N9 (Residues: 5-295; Coverage: 98%)
Gene names: CDA11, TATDN1
Sequence domains: TatD related DNase
Structure domains: Metal-dependent hydrolases

Ligands and Environments

3 bound ligands:
Ligand NA 1 x NA
Ligand NI 1 x NI
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 38.48Å b: 50.94Å c: 155.24Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.172 0.192
Expression system: Escherichia coli BL21(DE3)

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