› 2xky

Hybrid

Single particle analysis of Kir2.1NC_4 in negative stain

Released:
DOI: 10.2210/pdb2xky/pdb
PDB entry 2xky coloured by chain, front view.
PDB entry 2xky coloured by chain, side view.
PDB entry 2xky coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Self-directed assembly and clustering of the cytoplasmic domains of inwardly rectifying Kir2.1 potassium channels on association with PSD-95.
Fomina S, Howard TD, Sleator OK, Golovanova M, O'Ryan L, Leyland ML, Grossmann JG, Collins RF, Prince SM
Biochim Biophys Acta 1808 2374-89 (2011)
PMID: 21756874
Related structures: EMD-1764

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152949 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inward rectifier potassium channel 2 Chains: I, J, K, L
Molecule details ›
Chains: I, J, K, L
Length: 309 amino acids
Theoretical weight: 34.98 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P35561 (Residues: 1-67, 189-428; Coverage: 72%)
Gene names: Irk1, Kcnj2
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Experimental Method: X-ray solution scattering, Electron Microscopy
Resolution: 17.2Å
Relevant EMDB volumes: EMD-1764
Expression system: Escherichia coli BL21

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Citations

8 citation in other articles

Supertertiary structure of the synaptic MAGuK scaffold proteins is conserved.
McCann et al. (2012)
7 more