› 2xpw

X-ray diffraction
1.44Å resolution

TetR(D) in complex with oxytetracycline and magnesium.

Released:
DOI: 10.2210/pdb2xpw/pdb
PDB entry 2xpw coloured by chain, front view.
PDB entry 2xpw coloured by chain, side view.
PDB entry 2xpw coloured by chain, top view.
Source organism: Escherichia coli
Entry authors: Dalm D, Proft J, Palm GJ, Hinrichs W

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142298 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tetracycline repressor protein class D Chain: A
Molecule details ›
Chain: A
Length: 207 amino acids
Theoretical weight: 23.29 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P0ACT4 (Residues: 3-208; Coverage: 95%)
Gene name: tetR
Sequence domains:
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand OTC 1 x OTC
Ligand MG 1 x MG
Ligand CL 3 x CL
Ligand MES 1 x MES
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X31
Spacegroup: I4122
Unit cell:
a: 66.893Å b: 66.893Å c: 181.553Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.178 0.177 0.205
Expression system: Escherichia coli K-12

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