› 2xql

Electron Microscopy
19.5Å resolution

Fitting of the H2A-H2B histones in the electron microscopy map of the complex Nucleoplasmin:H2A-H2B histones (1:5).

Released:
DOI: 10.2210/pdb2xql/pdb
PDB entry 2xql coloured by chain, front view.
PDB entry 2xql coloured by chain, side view.
PDB entry 2xql coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Nucleoplasmin binds histone H2A-H2B dimers through its distal face.
Ramos I, Martín-Benito J, Finn R, Bretaña L, Aloria K, Arizmendi JM, Ausió J, Muga A, Valpuesta JM, Prado A
J Biol Chem 285 33771-8 (2010)
PMID: 20696766
Related structures: EMD-1777

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero decamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135436 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Histone H2A-IV Chains: A, C, E, G, I
Molecule details ›
Chains: A, C, E, G, I
Length: 91 amino acids
Theoretical weight: 10.03 KDa
Source organism: Gallus gallus
UniProt:
  • Canonical: P02263 (Residues: 16-106; Coverage: 71%)
Sequence domains:
Histone H2B 5 Chains: B, D, F, H, J
Molecule details ›
Chains: B, D, F, H, J
Length: 90 amino acids
Theoretical weight: 9.98 KDa
Source organism: Gallus gallus
UniProt:
  • Canonical: P0C1H4 (Residues: 37-126; Coverage: 71%)
Gene name: H2B-V
Sequence domains: Core histone H2A/H2B/H3/H4

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 19.5Å
Relevant EMDB volumes: EMD-1777

Quick links

Citations

5 review citations

Histone chaperone networks shaping chromatin function.
Hammond et al. (2017)
4 more

2 mentions without citation

Structure-function relationship of H2A-H2B specific plant histone chaperones.
Kumar et al. (2020)
1 more