› 2xv9

Solution NMR

The solution structure of ABA-1A saturated with oleic acid

Released:
DOI: 10.2210/pdb2xv9/pdb
PDB entry 2xv9 coloured by chain, ensemble of 20 models, front view.
PDB entry 2xv9 coloured by chain, ensemble of 20 models, side view.
PDB entry 2xv9 coloured by chain, ensemble of 20 models, top view.
Source organism: Ascaris suum
Primary publication:
Solution structure of a repeated unit of the ABA-1 nematode polyprotein allergen of Ascaris reveals a novel fold and two discrete lipid-binding sites.
Meenan NA, Ball G, Bromek K, Uhrín D, Cooper A, Kennedy MW, Smith BO
PLoS Negl Trop Dis 5 e1040 (2011)
PMID: 21526216

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170397 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ABA-1A1 repeat unit Chain: A
Molecule details ›
Chain: A
Length: 134 amino acids
Theoretical weight: 15.19 KDa
Source organism: Ascaris suum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q06811 (Residues: 1199-1327; Coverage: 10%)
Gene name: ABA-1
Sequence domains: Nematode polyprotein allergen ABA-1
Structure domains: Nematode polyprotein allergen ABA-1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 80%
Refinement method: DEFAULT
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

7 review citations

Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules.
Maizels et al. (2018)
6 more

3 mentions without citation

Structure of allergens and structure based epitope predictions.
Dall'antonia et al. (2014)
2 more