› 2xy1

X-ray diffraction
1.98Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127467 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neural cell adhesion molecule 2 Chain: A
Molecule details ›
Chain: A
Length: 192 amino acids
Theoretical weight: 21.28 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: O15394 (Residues: 209-398; Coverage: 23%)
Gene names: NCAM2, NCAM21
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P21
Unit cell:
a: 43.81Å b: 45.81Å c: 45.72Å
α: 90° β: 103.58° γ: 90°
R-values:
R R work R free
0.203 0.2 0.266
Expression system: Komagataella pastoris

Quick links

Citations

5 review citations

Polysialic acid: biosynthesis, novel functions and applications.
Colley et al. (2014)
4 more

2 mentions without citation

Chondroitin sulfate proteoglycans: structure-function relationship with implication in neural development and brain disorders.
Avram et al. (2014)
1 more