› 2xy2

X-ray diffraction
1.82Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127467 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neural cell adhesion molecule 2 Chain: A
Molecule details ›
Chain: A
Length: 189 amino acids
Theoretical weight: 21.2 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: O15394 (Residues: 19-207; Coverage: 23%)
Gene names: NCAM2, NCAM21
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
Ligand NAG 1 x NAG
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I911-5
Spacegroup: P3121
Unit cell:
a: 42.06Å b: 42.06Å c: 202.91Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.205 0.203 0.24
Expression system: Komagataella pastoris

Quick links

Citations

6 review citations

Polysialic acid: biosynthesis, novel functions and applications.
Colley et al. (2014)
5 more

1 mention without citation

The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
Chakraborty et al. (2013)