› 2y1h

X-ray diffraction
2.5Å resolution

Crystal structure of the human TatD-domain protein 3 (TATDN3)

Released:
DOI: 10.2210/pdb2y1h/pdb
PDB entry 2y1h coloured by chain, front view.
PDB entry 2y1h coloured by chain, side view.
PDB entry 2y1h coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Muniz JRC, Puranik S, Krojer T, Yue WW, Ugochukwu E, Filippakopoulos P, von Delft F, Arrowsmith CH, Edwards AM, Weigelt J, Bountra C, Kavanagh KL, Oppermann U

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172642 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative deoxyribonuclease TATDN3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 272 amino acids
Theoretical weight: 30.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q17R31 (Residues: 5-274; Coverage: 99%)
Gene name: TATDN3
Sequence domains: TatD related DNase
Structure domains: Metal-dependent hydrolases

Ligands and Environments

4 bound ligands:
Ligand ZN 4 x ZN
Ligand PO4 2 x PO4
Ligand NI 2 x NI
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P31
Unit cell:
a: 44.91Å b: 44.91Å c: 233.112Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.18 0.177 0.218
Expression system: Escherichia coli BL21(DE3)

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