› 2y5i

X-ray diffraction
2.03Å resolution

S100Z from zebrafish in complex with calcium

Released:
DOI: 10.2210/pdb2y5i/pdb
PDB entry 2y5i coloured by chain, front view.
PDB entry 2y5i coloured by chain, side view.
PDB entry 2y5i coloured by chain, top view.
Source organism: Danio rerio
Primary publication:
The crystal structure of zebrafish S100Z: implications for calcium-promoted S100 protein oligomerisation.
Moroz OV, Bronstein IB, Wilson KS
J Mol Biol 411 1072-82 (2011)
PMID: 21756915

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175874 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein S100-Z Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 99 amino acids
Theoretical weight: 11.25 KDa
Source organism: Danio rerio
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q503K9 (Residues: 1-99; Coverage: 100%)
Gene name: s100z
Sequence domains: S-100/ICaBP type calcium binding domain
Structure domains: EF-hand

Ligands and Environments

2 bound ligands:
Ligand CA 12 x CA
Ligand IPA 6 x IPA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P21212
Unit cell:
a: 75.611Å b: 132.25Å c: 58.209Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.171 0.227
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Building the niche: the role of the S100 proteins in metastatic growth.
Lukanidin et al. (2012)
2 other articles

3 mentions without citation

Multiple Evolutionary Origins of Ubiquitous Cu2+ and Zn2+ Binding in the S100 Protein Family.
Wheeler et al. (2016)
2 more