› 2y95

Solution NMR

Solution structure of AUCG tetraloop hairpin found in human Xist RNA A-repeats essential for X-inactivation

Released:
DOI: 10.2210/pdb2y95/pdb
PDB entry 2y95 coloured by chain, ensemble of 10 models, front view.
PDB entry 2y95 coloured by chain, ensemble of 10 models, side view.
PDB entry 2y95 coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization.
Duszczyk MM, Wutz A, Rybin V, Sattler M
RNA 17 1973-82 (2011)
PMID: 21947263

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196604 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
5'-R(*GP*GP*CP*GP*CP*AP*UP*CP*GP*GP*CP*GP*CP*C)-3' Chain: A
Molecule details ›
Chain: A
Length: 14 nucleotides
Theoretical weight: 4.49 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 74%
Refinement method: ARIA
Expression system: Not provided

Quick links

Citations

22 review citations

Gene regulation by long non-coding RNAs and its biological functions.
Statello et al. (2021)
21 more

5 mentions without citation

The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization.
Duszczyk et al. (2011)
4 more