› 2yeo

X-ray diffraction
1.08Å resolution

A39L mutation of scorpion toxin lqh-alpha-it

Released:
DOI: 10.2210/pdb2yeo/pdb
PDB entry 2yeo coloured by chain, front view.
PDB entry 2yeo coloured by chain, side view.
PDB entry 2yeo coloured by chain, top view.
Source organism: Leiurus quinquestriatus hebraeus
Entry authors: Frolow F, Kahn R, Gurevitz M

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148150 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-insect toxin LqhaIT Chain: A
Molecule details ›
Chain: A
Length: 65 amino acids
Theoretical weight: 7.44 KDa
Source organism: Leiurus quinquestriatus hebraeus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P17728 (Residues: 20-83; Coverage: 97%)
Sequence domains: Scorpion toxin-like domain
Structure domains: Knottin, scorpion toxin-like

Ligands and Environments

4 bound ligands:
Ligand DR8 1 x DR8
Ligand DR0 1 x DR0
Ligand EDO 4 x EDO
Ligand CL 3 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: F432
Unit cell:
a: 129.707Å b: 129.707Å c: 129.707Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.12 0.12 0.123
Expression system: Escherichia coli BL21

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