› 2yhm

X-ray diffraction
3.6Å resolution

Structure of respiratory syncytial virus nucleocapsid protein, P212121 crystal form

Released:
DOI: 10.2210/pdb2yhm/pdb
Model geometry
Fit model/data
PDB entry 2yhm coloured by chain, front view.
PDB entry 2yhm coloured by chain, side view.
PDB entry 2yhm coloured by chain, top view.
Source organisms:
Primary publication:
Structures of respiratory syncytial virus nucleocapsid protein from two crystal forms: details of potential packing interactions in the native helical form.
El Omari K, Dhaliwal B, Ren J, Abrescia NG, Lockyer M, Powell KL, Hawkins AR, Stammers DK
Acta Crystallogr Sect F Struct Biol Cryst Commun 67 1179-83 (2011)
PMID: 22102022

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
hetero undecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136971 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Nucleoprotein Chains: A, B, C, D, E, F, G, H, I, J
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 375 amino acids
Theoretical weight: 41.66 KDa
Source organism: Human orthopneumovirus
Expression system: Escherichia coli
UniProt:
  • Canonical: P03418 (Residues: 1-375; Coverage: 96%)
Gene name: N
Sequence domains: Pneumovirus nucleocapsid protein
RNA Chain: K
Molecule details ›
Chain: K
Length: 70 nucleotides
Theoretical weight: 21.32 KDa
Source organism: Escherichia coli

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P212121
Unit cell:
a: 133.607Å b: 149.914Å c: 255.196Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.196 0.224
Expression system: Escherichia coli

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Citations

7 review citations

Structure unifies the viral universe.
Abrescia et al. (2012)
6 more

1 mention without citation

Structures of respiratory syncytial virus nucleocapsid protein from two crystal forms: details of potential packing interactions in the native helical form.
El Omari et al. (2011)