› 2yj7

X-ray diffraction
1.65Å resolution

Crystal structure of a hyperstable protein from the Precambrian period

Released:
DOI: 10.2210/pdb2yj7/pdb
PDB entry 2yj7 coloured by chain, front view.
PDB entry 2yj7 coloured by chain, side view.
PDB entry 2yj7 coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Conservation of protein structure over four billion years.
Ingles-Prieto A, Ibarra-Molero B, Delgado-Delgado A, Perez-Jimenez R, Fernandez JM, Gaucher EA, Sanchez-Ruiz JM, Gavira JA
Structure 21 1690-7 (2013)
PMID: 23932589

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163364 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
LPBCA THIOREDOXIN Chains: A, B
Molecule details ›
Chains: A, B
Length: 106 amino acids
Theoretical weight: 12.01 KDa
Source organism: synthetic construct
Expression system: Escherichia coli BL21(DE3)
Structure domains: Glutaredoxin

Ligands and Environments

1 bound ligand:
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P21
Unit cell:
a: 55.072Å b: 30.189Å c: 59.004Å
α: 90° β: 116.81° γ: 90°
R-values:
R R work R free
0.184 0.182 0.22
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

8 review citations

Computational methods in drug discovery.
Leelananda et al. (2016)
7 more

7 mentions without citation

Conservation of protein structure over four billion years.
Ingles-Prieto et al. (2013)
6 more