› 2ykd

X-ray diffraction
1.86Å resolution

Structure of the matrix protein from human respiratory syncytial virus

Released:
DOI: 10.2210/pdb2ykd/pdb
PDB entry 2ykd coloured by chain, front view.
PDB entry 2ykd coloured by chain, side view.
PDB entry 2ykd coloured by chain, top view.
Source organism: Human orthopneumovirus
Primary publication:
Influence of lipids on the interfacial disposition of respiratory syncytical virus matrix protein.
McPhee HK, Carlisle JL, Beeby A, Money VA, Watson SM, Yeo RP, Sanderson JM
Langmuir 27 304-11 (2011)
PMID: 21141948

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143666 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Matrix protein Chain: A
Molecule details ›
Chain: A
Length: 257 amino acids
Theoretical weight: 28.86 KDa
Source organism: Human orthopneumovirus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P0DOE7 (Residues: 1-256; Coverage: 100%)
Gene name: M
Sequence domains: Pneumovirus matrix protein
Structure domains: HRSV-S2 matrix protein, N-terminal domain

Ligands and Environments

1 bound ligand:
Ligand ACT 2 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: C2
Unit cell:
a: 52.402Å b: 78.902Å c: 65.827Å
α: 90° β: 96.18° γ: 90°
R-values:
R R work R free
0.182 0.18 0.229
Expression system: Escherichia coli BL21

Quick links

Citations

3 review citations

Paramyxovirus glycoprotein incorporation, assembly and budding: a three way dance for infectious particle production.
El Najjar et al. (2014)
2 more

1 mention without citation

Structure and self-assembly of the calcium binding matrix protein of human metapneumovirus.
Leyrat et al. (2014)