› 2yok

X-ray diffraction
1.67Å resolution

Function and Biology Details

Reaction catalysed: 
Hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192870 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Exoglucanase 1 Chain: A
Molecule details ›
Chain: A
Length: 426 amino acids
Theoretical weight: 45.15 KDa
Source organism: Trichoderma harzianum
UniProt:
  • Canonical: Q9P8P3 (Residues: 18-443; Coverage: 87%)
Gene name: cbh1
Sequence domains: Glycosyl hydrolase family 7
Structure domains: Glycoside hydrolase, family 7, domain

Ligands and Environments

3 bound ligands:
Ligand NAG 3 x NAG
Ligand PE4 1 x PE4
Ligand PEG 1 x PEG
1 modified residue:
Ligand PCA 1 x PCA

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE W01B-MX2
Spacegroup: P212121
Unit cell:
a: 56.734Å b: 69.187Å c: 90.569Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.13 0.129 0.161

Quick links

Citations

1 review citation

Mini-review: Brazilian fungi diversity for biomass degradation.
Valencia et al. (2013)
13 other articles

4 mentions without citation

Correlation of structure, function and protein dynamics in GH7 cellobiohydrolases from Trichoderma atroviride, T. reesei and T. harzianum.
Borisova et al. (2018)
3 more