› 2yop

X-ray diffraction
2.3Å resolution

Long wavelength S-SAD structure of FAM3B PANDER

Released:
DOI: 10.2210/pdb2yop/pdb
PDB entry 2yop coloured by chain, front view.
PDB entry 2yop coloured by chain, side view.
PDB entry 2yop coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
FAM3B PANDER and FAM3C ILEI represent a distinct class of signaling molecules with a non-cytokine-like fold.
Johansson P, Bernström J, Gorman T, Oster L, Bäckström S, Schweikart F, Xu B, Xue Y, Schiavone LH
Structure 21 306-13 (2013)
PMID: 23333428

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190047 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein FAM3B Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 198 amino acids
Theoretical weight: 22.16 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9D309 (Residues: 46-235; Coverage: 92%)
Gene names: Fam3b, ORF9
Sequence domains: Interleukin-like EMT inducer

Ligands and Environments

1 bound ligand:
Ligand GOL 3 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P212121
Unit cell:
a: 42.93Å b: 90.44Å c: 185.28Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.185 0.229
Expression system: Homo sapiens

Quick links

Citations

13 citation in other articles

ILEI: a novel marker for epithelial-mesenchymal transition and poor prognosis in colorectal cancer.
Gao et al. (2014)
12 more

1 mention without citation

The interleukin-like epithelial-mesenchymal transition inducer ILEI exhibits a non-interleukin-like fold and is active as a domain-swapped dimer.
Jansson et al. (2017)