2yz8

X-ray diffraction
2Å resolution

Crystal structure of the 32th Ig-like domain of human obscurin (KIAA1556)

Released:
Source organism: Homo sapiens
Entry authors: Saijo S, Ohsawa N, Nishino A, Kishishita S, Chen L, Fu ZQ, Chrzas J, Wang BC, Shirouzu M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178427 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Obscurin Chain: A
Molecule details ›
Chain: A
Length: 103 amino acids
Theoretical weight: 10.84 KDa
Source organism: Homo sapiens
Expression system: Cell-free protein synthesis
UniProt:
  • Canonical: Q5VST9 (Residues: 3184-3273; Coverage: 1%)
Gene names: KIAA1556, KIAA1639, OBSCN
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: P43212
Unit cell:
a: 43.358Å b: 43.358Å c: 102.316Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.209 0.261
Expression system: Cell-free protein synthesis