› 2z0a

X-ray diffraction
1.85Å resolution

Crystal structure of RNA-binding domain of NS1 from influenza A virus A/crow/Kyoto/T1/2004(H5N1)

Released:
DOI: 10.2210/pdb2z0a/pdb
PDB entry 2z0a coloured by chain, front view.
PDB entry 2z0a coloured by chain, side view.
PDB entry 2z0a coloured by chain, top view.
Source organism: Influenza A virus
Entry authors: Saijo S, Kishishita S, Kamo-Uchikubo T, Terada T, Shirouzu M, Ito H, Ito T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177169 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Non-structural protein 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 79 amino acids
Theoretical weight: 8.84 KDa
Source organism: Influenza A virus
Expression system: Cell-free protein synthesis
UniProt:
  • Canonical: Q5H7J4 (Residues: 1-72; Coverage: 32%)
Gene names: NS, NS1
Sequence domains: Influenza non-structural protein (NS1)
Structure domains: S15/NS1, RNA-binding

Ligands and Environments

2 bound ligands:
Ligand GLY 4 x GLY
Ligand SIN 2 x SIN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P21
Unit cell:
a: 37.723Å b: 54.378Å c: 66.347Å
α: 90° β: 100.57° γ: 90°
R-values:
R R work R free
0.176 0.172 0.238
Expression system: Cell-free protein synthesis

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