› 2z36

X-ray diffraction
2.8Å resolution

Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105)

Released:
DOI: 10.2210/pdb2z36/pdb
PDB entry 2z36 coloured by chain, front view.
PDB entry 2z36 coloured by chain, side view.
PDB entry 2z36 coloured by chain, top view.
Source organism: Nonomuraea recticatena
Primary publication:
Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105).
Yasutake Y, Imoto N, Fujii Y, Fujii T, Arisawa A, Tamura T
Biochem Biophys Res Commun 361 876-82 (2007)
PMID: 17679139

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173699 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytochrome P450 type compactin 3'',4''-hydroxylase Chains: A, B
Molecule details ›
Chains: A, B
Length: 413 amino acids
Theoretical weight: 45.89 KDa
Source organism: Nonomuraea recticatena
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q2L6S8 (Residues: 1-407; Coverage: 100%)
Gene name: moxA
Sequence domains: Cytochrome P450
Structure domains: Cytochrome P450

Ligands and Environments

3 bound ligands:
Ligand FE 2 x FE
Ligand HEM 2 x HEM
Ligand MES 2 x MES
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P212121
Unit cell:
a: 81.557Å b: 83.256Å c: 175.851Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.23 0.23 0.274
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Diversity of P450 enzymes in the biosynthesis of natural products.
Podust et al. (2012)
2 more

10 mentions without citation

Conformational plasticity and structure/function relationships in cytochromes P450.
Pochapsky et al. (2010)
9 more