› 2z7a

X-ray diffraction
2.1Å resolution

X-ray crystal structure of RV0760c from Mycobacterium tuberculosis at 2.10 Angstrom resolution

Released:
DOI: 10.2210/pdb2z7a/pdb
PDB entry 2z7a coloured by chain, front view.
PDB entry 2z7a coloured by chain, side view.
PDB entry 2z7a coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Primary publication:
Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase.
Cherney MM, Garen CR, James MN
Biochim Biophys Acta 1784 1625-32 (2008)
PMID: 18589008

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-159819 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nuclear transport factor 2 domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 139 amino acids
Theoretical weight: 15.26 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
  • Canonical: P71817 (Residues: 1-139; Coverage: 100%)
Gene name: MT0785
Sequence domains: Nuclear transport factor 2 (NTF2) domain
Structure domains: Nuclear Transport Factor 2; Chain: A,

Ligands and Environments

1 bound ligand:
Ligand ACT 4 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P212121
Unit cell:
a: 38.968Å b: 83.239Å c: 164.691Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.195 0.251
Expression system: Escherichia coli

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Citations

4 citation in other articles

High-performance prediction of functional residues in proteins with machine learning and computed input features.
Somarowthu et al. (2011)
3 more