› 2z84

X-ray diffraction
1.7Å resolution

Insights from crystal and solution structures of mouse UfSP1

Released:
DOI: 10.2210/pdb2z84/pdb
PDB entry 2z84 coloured by chain, front view.
PDB entry 2z84 coloured by chain, side view.
PDB entry 2z84 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural basis for Ufm1 processing by UfSP1.
Ha BH, Ahn HC, Kang SH, Tanaka K, Chung CH, Kim EE
J Biol Chem 283 14893-900 (2008)
PMID: 18321862

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190029 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ufm1-specific protease 1 Chain: A
Molecule details ›
Chain: A
Length: 218 amino acids
Theoretical weight: 23.8 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9CZP0 (Residues: 6-215; Coverage: 97%)
Gene names: D5Ertd655e, Ufsp1
Sequence domains: Peptidase family C78
Structure domains: Cathepsin B; Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: R32
Unit cell:
a: 71.704Å b: 71.704Å c: 209.228Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.188 0.186 0.227
Expression system: Escherichia coli

Quick links

Citations

8 review citations

The UFMylation System in Proteostasis and Beyond.
Gerakis et al. (2019)
7 more

2 mentions without citation

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.
Kwasna et al. (2018)
1 more