› 2zfi

X-ray diffraction
1.55Å resolution

Crystal Structure of the Kif1A Motor Domain Before Mg Release

Released:
DOI: 10.2210/pdb2zfi/pdb
PDB entry 2zfi coloured by chain, front view.
PDB entry 2zfi coloured by chain, side view.
PDB entry 2zfi coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural model for strain-dependent microtubule activation of Mg-ADP release from kinesin.
Nitta R, Okada Y, Hirokawa N
Nat Struct Mol Biol 15 1067-75 (2008)
PMID: 18806800

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152547 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin-like protein KIF1A Chain: A
Molecule details ›
Chain: A
Length: 366 amino acids
Theoretical weight: 41.13 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P33173 (Residues: 1-361; Coverage: 21%)
Gene names: Atsv, Kif1, Kif1a
Sequence domains: Kinesin motor domain
Structure domains: Kinesin motor domain

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand ADP 1 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P212121
Unit cell:
a: 41.722Å b: 52.312Å c: 157.26Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.199 0.224
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Prime movers: the mechanochemistry of mitotic kinesins.
Cross et al. (2014)
7 more

5 mentions without citation

Rab6 regulation of the kinesin family KIF1C motor domain contributes to Golgi tethering.
Lee et al. (2015)
4 more