Function and Biology Details
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137015 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Polymerase acidic protein
Molecule details ›
Chain: A
Length: 478 amino acids
Theoretical weight: 54.71 KDa
Source organism: Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Expression system: Escherichia coli
UniProt:
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PA
Length: 478 amino acids
Theoretical weight: 54.71 KDa
Source organism: Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Expression system: Escherichia coli
UniProt:
- Canonical:
P03433 (Residues: 239-716; Coverage: 67%)
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PA
RNA-directed RNA polymerase catalytic subunit
Molecule details ›
Chain: B
Length: 81 amino acids
Theoretical weight: 8.82 KDa
Source organism: Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Expression system: Escherichia coli
UniProt:
Length: 81 amino acids
Theoretical weight: 8.82 KDa
Source organism: Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Expression system: Escherichia coli
UniProt:
- Canonical: P03431 (Residues: 1-81; Coverage: 11%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SPRING-8 BEAMLINE BL41XU
Spacegroup:
P3221
Expression system: Escherichia coli
