› 2zqe

X-ray diffraction
1.7Å resolution

Crystal structure of the Smr domain of Thermus thermophilus MutS2

Released:
DOI: 10.2210/pdb2zqe/pdb
PDB entry 2zqe coloured by chain, front view.
PDB entry 2zqe coloured by chain, side view.
PDB entry 2zqe coloured by chain, top view.
Source organism: Thermus thermophilus HB8
Primary publication:
Crystal structure of MutS2 endonuclease domain and the mechanism of homologous recombination suppression.
Fukui K, Nakagawa N, Kitamura Y, Nishida Y, Masui R, Kuramitsu S
J Biol Chem 283 33417-27 (2008)
PMID: 18838375

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177897 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endonuclease MutS2 Chain: A
Molecule details ›
Chain: A
Length: 83 amino acids
Theoretical weight: 8.95 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5SHT5 (Residues: 663-744; Coverage: 11%)
Gene names: TTHA1645, mutS2
Sequence domains: Smr domain
Structure domains: Ribosomal Protein S8; Chain: A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P21212
Unit cell:
a: 48.813Å b: 54.216Å c: 30.243Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.189 0.227
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Postreplicative mismatch repair.
Jiricny J. (2013)
2 more

3 mentions without citation

Macromolecular ab initio phasing enforcing secondary and tertiary structure.
Millán et al. (2015)
2 more