› 307d

X-ray diffraction
1.85Å resolution

Structure of a DNA analog of the primer for HIV-1 RT second strand synthesis

Released:
DOI: 10.2210/pdb307d/pdb
Model geometry
Fit model/data
PDB entry 307d coloured by chain, front view.
PDB entry 307d coloured by chain, side view.
PDB entry 307d coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Structure of a DNA analog of the primer for HIV-1 RT second strand synthesis.
Han GW, Kopka ML, Cascio D, Grzeskowiak K, Dickerson RE
J Mol Biol 269 811-26 (1997)
PMID: 9223643

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115982 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA (5'-D(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3') Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 10 nucleotides
Theoretical weight: 3.1 KDa
Source organism: Synthetic construct
Expression system: Not provided
DNA (5'-D(*CP*TP*TP*TP*TP*CP*TP*TP*TP*G)-3') Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 10 nucleotides
Theoretical weight: 2.99 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: RIGAKU RU200
Spacegroup: C2
Unit cell:
a: 59.82Å b: 28.28Å c: 72.49Å
α: 90° β: 103.87° γ: 90°
R-values:
R R work R free
0.233 not available not available
Expression system: Not provided

Quick links

Citations

2 review citations

Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition.
Sarafianos et al. (2009)
1 more

4 mentions without citation

DNA conformations and their sequence preferences.
Svozil et al. (2008)
3 more