› 329d

X-ray diffraction
2.7Å resolution

EFFECT OF CYTOSINE METHYLATION ON DNA-DNA RECOGNITION AT CPG STEPS

Released:
DOI: 10.2210/pdb329d/pdb
PDB entry 329d coloured by chain, front view.
PDB entry 329d coloured by chain, side view.
PDB entry 329d coloured by chain, top view.
Source organism: Unidentified
Primary publication:
Effect of cytosine methylation on DNA-DNA recognition at CpG steps.
Mayer-Jung C, Moras D, Timsit Y
J Mol Biol 270 328-35 (1997)
PMID: 9237900

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-116002 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA (5'-D(*AP*CP*CP*GP*CP*(5CM)P*GP*GP*CP*GP*CP*C)-3') Chain: A
Molecule details ›
Chain: A
Length: 12 nucleotides
Theoretical weight: 3.62 KDa
Source organism: Unidentified
Expression system: Not provided
DNA (5'-D(*GP*GP*CP*GP*CP*(5CM)P*GP*GP*CP*GP*GP*T)-3') Chain: B
Molecule details ›
Chain: B
Length: 12 nucleotides
Theoretical weight: 3.73 KDa
Source organism: Unidentified
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand 5CM 2 x 5CM

Experiments and Validation Details

Entry percentile scores
Spacegroup: R3
Unit cell:
a: 65.53Å b: 65.53Å c: 46.35Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.191 0.191 not available
Expression system: Not provided

Quick links

Citations

3 review citations

DNA methylation in the immune system.
Teitell et al. (2003)
2 more

1 mention without citation

Evolved DNA Duplex Readers for Strand-Asymmetrically Modified 5-Hydroxymethylcytosine/5-Methylcytosine CpG Dyads.
Buchmuller et al. (2022)