› 359d

X-ray diffraction
2.9Å resolution

INHIBITION OF THE HAMMERHEAD RIBOZYME CLEAVAGE REACTION BY SITE-SPECIFIC BINDING OF TB(III)

Released:
DOI: 10.2210/pdb359d/pdb
PDB entry 359d coloured by chain, front view.
PDB entry 359d coloured by chain, side view.
PDB entry 359d coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Inhibition of the hammerhead ribozyme cleavage reaction by site-specific binding of Tb.
Feig AL, Scott WG, Uhlenbeck OC
Science 279 81-4 (1998)
PMID: 9417029

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196617 (preferred)
Entry contents:
2 distinct RNA molecules
Macromolecules (2 distinct):
RNA HAMMERHEAD RIBOZYME Chain: A
Molecule details ›
Chain: A
Length: 16 nucleotides
Theoretical weight: 5.17 KDa
Source organism: Synthetic construct
Expression system: Not provided
RNA HAMMERHEAD RIBOZYME Chain: B
Molecule details ›
Chain: B
Length: 25 nucleotides
Theoretical weight: 8.02 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand TB 5 x TB
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P3121
Unit cell:
a: 65.54Å b: 65.54Å c: 138.08Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.256 0.256 0.302
Expression system: Not provided

Quick links

Citations

15 review citations

RNA Structural Dynamics As Captured by Molecular Simulations: A Comprehensive Overview.
Šponer et al. (2018)
14 more

5 mentions without citation

MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes.
Davis et al. (2004)
4 more