› 383d

X-ray diffraction
1.7Å resolution

Hydration and recognition of methylated CPG steps in DNA

Released:
DOI: 10.2210/pdb383d/pdb
PDB entry 383d coloured by chain, front view.
PDB entry 383d coloured by chain, side view.
PDB entry 383d coloured by chain, top view.
Source organism: Unidentified
Primary publication:
Hydration and recognition of methylated CpG steps in DNA.
Mayer-Jung C, Moras D, Timsit Y
EMBO J 17 2709-18 (1998)
PMID: 9564052

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-116041 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*(5CM)P*GP*CP*(5CM)P*GP*GP*(5CM)P*GP*G)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 10 nucleotides
Theoretical weight: 3.09 KDa
Source organism: Unidentified
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand MG 1 x MG
1 modified residue:
Ligand 5CM 6 x 5CM

Experiments and Validation Details

Entry percentile scores
X-ray source: LURE BEAMLINE DW32
Spacegroup: P212121
Unit cell:
a: 23.9Å b: 45.3Å c: 46.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.196 not available
Expression system: Not provided

Quick links

Citations

6 review citations

Evolving insights on how cytosine methylation affects protein-DNA binding.
Dantas Machado et al. (2015)
5 more

5 mentions without citation

Writing and rewriting the epigenetic code of cancer cells: from engineered proteins to small molecules.
Blancafort et al. (2013)
4 more