› 3a02

X-ray diffraction
1Å resolution

Crystal structure of Aristaless homeodomain

Released:
DOI: 10.2210/pdb3a02/pdb
PDB entry 3a02 coloured by chain, front view.
PDB entry 3a02 coloured by chain, side view.
PDB entry 3a02 coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless.
Miyazono K, Zhi Y, Takamura Y, Nagata K, Saigo K, Kojima T, Tanokura M
EMBO J 29 1613-23 (2010)
PMID: 20389279

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170345 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Homeobox protein aristaless Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 7.3 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: Q06453 (Residues: 91-146; Coverage: 14%)
Gene names: CG3935, al
Sequence domains: Homeodomain
Structure domains: Homeodomain-like

Ligands and Environments

2 bound ligands:
Ligand CD 1 x CD
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P3221
Unit cell:
a: 45.81Å b: 45.81Å c: 48.98Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.173 0.172 0.184
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Investigating Developmental and Epileptic Encephalopathy Using Drosophila melanogaster.
Takai et al. (2020)
22 other articles

5 mentions without citation

Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless.
Miyazono et al. (2010)
4 more