› 3a1s

X-ray diffraction
1.5Å resolution

Crystal structue of the cytosolic domain of T. maritima FeoB iron iransporter in GDP form I

Released:
DOI: 10.2210/pdb3a1s/pdb
PDB entry 3a1s coloured by chain, front view.
PDB entry 3a1s coloured by chain, side view.
PDB entry 3a1s coloured by chain, top view.
Source organism: Thermotoga maritima
Primary publication:
Structural basis of novel interactions between the small-GTPase and GDI-like domains in prokaryotic FeoB iron transporter.
Hattori M, Jin Y, Nishimasu H, Tanaka Y, Mochizuki M, Uchiumi T, Ishitani R, Ito K, Nureki O
Structure 17 1345-55 (2009)
PMID: 19733088

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194430 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferrous iron transport protein B Chains: A, B
Molecule details ›
Chains: A, B
Length: 258 amino acids
Theoretical weight: 29.47 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9WXQ8 (Residues: 17-269; Coverage: 38%)
Gene name: TM_0051
Sequence domains:
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand GDP 2 x GDP
Ligand MG 2 x MG
Ligand MRD 1 x MRD
Ligand MPD 2 x MPD
1 modified residue:
Ligand MSE 10 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P21212
Unit cell:
a: 107.166Å b: 109.723Å c: 46.496Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.171 0.217
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Structure-function relationships of the G domain, a canonical switch motif.
Wittinghofer et al. (2011)
3 more

2 mentions without citation

Ins and Outs: Recent Advancements in Membrane Protein-Mediated Prokaryotic Ferrous Iron Transport.
Brown et al. (2021)
1 more